Description
Clinical History
There are no details of the clinical history.
Pathology
The specimens from this case consists of two segments of sigmoid colon. The mucosa of the bowel is studded with numerous sessile and pedunculated partially pigmented polyps up to 1.5 cm in maximum diameter. There is no macroscopic evidence of malignant change.
Note
Microscopically, the polyps are most commonly tubular adenomas (>75% have a tubular structure; also called adenomatous polyps). Less frequently, they are villous adenomas (>75% have villous morphology) or tubulovillous adenomas (25-75% villous). They can have varying grades of dysplasia. The histological appearances are identical to sporadic colonic adenomas.
Patients with familial adenomatous polyposis (FAP; a form of hereditary colon cancer syndrome involving the APC gene located on chromosome 5q21) are offered prophylactic colectomy because invasive adenocarcinoma is almost certain to develop in one or more of the polyps, usually about 15 years after the onset of the adenomatosis. This condition is transmitted as an autosomal dominant trait.
Advantages
- Anatomically accurate and identical to real specimen
- No ethical issues - not real human body parts
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- Available within a short lead time
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Human Cadavers
- Access to cadavers can be problematic. Many countries cannot access cadavers for cultural and religious reasons
- Cadavers cost a lot money
- High cost for establishing your own plastination suite
- Wet specimens cannot be used in uncertified labs
- Dissection of cadavers is a lot of staff time and that is a cost
- Storage of cadaver material needs special refrigeration etc. which has coast
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Plastinates
- Costs
- Ethical issues
- Timeframe for plastination process
- Many countries do not allow their importation
- One of a kind
Superior 3D print results compared with conventional methods
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Clear Support Material
- To avoid breakage of fragile, thin, and delicate arteries, veins or vessels, a clear support material is printed on such spots. This makes the models robust and can be handled by students easily.
